Comparative Study Among Ephedrine, Norepinephrine and Phenylephrine Infusions to Prevent Spinal Hypotension During Cesarean Section. A Randomized Controlled Double-Blind Study

Background: Spinal anesthesia is the recommended technique in elective cesarean sections. Usage of vasopressors more widely accepted as an effective method for decreasing postspinal hypotension than fluid loading. However, ideal vasopressor to prevent spinal during section has been a subject much debate. It should maintain maternal blood pressure and placental perfusion, with minimal adverse effect on fetus mother.Aim: The primary aim was compare prophylactic infusion phenylephrine versus norepinephrine ephedrine prevention section. secondary assess their effects neonate.Methods: Seventy-five patients were enrolled this study randomly divided into three groups. Group P received group N infusion, while E infusion. changes mean arterial heart rate recorded throughout surgery. Maternal neonatal perioperative complications controlled recorded.Results: MAP higher tachycardia significantly common ephedrine, bradycardia without significant difference. Nausea vomiting group. Neonatal acidosis lesser groups group.Conclusion: Prophylactic can be successfully used parturient undergoing less drawbacks fetal well-being ephedrine.